Prolonged survival in patients with local chronic infection after high-grade glioma treatment: Two case reports

Prolonged survival in patients with local chronic infection after high-grade glioma treatment: Two case reports

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High-grade gliomas are primary brain tumors with poor prognosis, despite surgical treatment followed by radiotherapy and concomitant chemotherapy.We present two cases of long-term survival in patients treated for high-grade glioma and concomitant prolonged bacterial wound infection.The first patient Gift Wrap treated for glioblastoma IDH-wildtype had been without disease progression for 61 months from the first resected recurrence.

Despite incomplete chemotherapy-induced myelosuppression in the second patient with anaplastic astrocytoma IDH-mutant, she died without disease relapse after 14 years from the diagnosis due Bag to other comorbidities.We assume that the documented prolonged survival could be related to the bacterial infection.